
Selective Dorsal Cryoablation (SDC) for Premature Ejaculation: Science, Safety, and Patient Benefits
Selective Dorsal Cryoablation
Premature ejaculation (PE) is one of the most common sexual health concerns in men. Affecting up to 1 in 3 men worldwide, it often leads to stress, anxiety, and relationship difficulties. While traditional treatments such as creams, pills, and therapy provide temporary help, they rarely offer a long-term solution. Selective Dorsal Cryoablation (SDC) has emerged as a modern, effective alternative for lasting results.
A new approach called Selective Dorsal Cryoablation (SDC) is gaining attention for its ability to directly target penile nerves, reduce hypersensitivity, and provide long-lasting improvement. Though the method sounds highly technical, its foundation lies in a medical technology that has been studied for decades — cryoablation.
This article explains the history, science, and clinical results of cryoablation, and why SDC is considered one of the most promising modern treatments for premature ejaculation.
Introduction
Premature ejaculation (PE) is one of the most common male sexual health concerns. It affects nearly 1 in 3 men worldwide. This condition often leads to stress, anxiety, and relationship challenges.
Traditional methods, including pills, creams, and therapy, bring only temporary results. They rarely provide long-term improvement. However, a modern solution called Selective Dorsal Cryoablation (SDC) directly targets penile nerves. It reduces hypersensitivity and provides lasting benefits.
A Brief History of Cryoablation
Cryoablation, meaning “destroying with cold,” is a proven medical technique. It was first studied in the 1960s.
- 1961: Dr. Cooper used liquid nitrogen for nerve cryotherapy.
- 1967: Dr. Amoils applied CO₂ and N₂O for safer cryosurgery.
- 1976: Dr. Lloyd discovered reversible demyelination, without permanent damage or neuroma.
Since then, cryoablation has been applied in cardiology, oncology, and pain management. Over time, doctors adapted this method for sexual health, specifically premature ejaculation.
The Science of Cryoablation
Cryoablation works through the Joule-Thompson effect. Compressed gases rapidly expand and cool, forming an ice ball at the probe tip.
When applied to the dorsal penile nerve:
- The myelin sheath freezes temporarily.
- Nerve conduction stops, reducing sensitivity.
- Over months, nerves regenerate, allowing the brain to reset ejaculation reflexes.
Unlike topical anesthetics, the effect lasts months or years.
First Use in Premature Ejaculation
In 2013, Dr. David Prologo first applied cryoablation for PE.
Study details:
- 24 men with lifelong PE participated.
- CT-guided imaging localized the dorsal penile nerve.
- Two freezing cycles were applied.
Results:
- IELT rose from 54.7 to 256 seconds in one week.
- At 6 months, IELT stabilized at 182.5 seconds.
- Side effects were mild and temporary, including slight rigidity changes or tingling.
These results confirmed safety and long-term effectiveness.
How Modern SDC Works
Today, SDC uses ultrasound-guided precision. The procedure is quick and minimally invasive.
Step-by-step:
- Preparation: Local anesthesia and ultrasound mapping.
- Probe placement: A fine cryoprobe enters near the penile root.
- Freezing cycles: Probe cooled to –78°C, repeated bilaterally.
- Completion: Warm saline protects tissues, and the patient leaves in 30 minutes.
Benefits:
- No stitches or incisions.
- Minimal pain and same-day recovery.
- Same-day return to sexual activity.
Safety and Risks
While SDC is safe, minor side effects may occur.
- Temporary numbness in the glans.
- Minor bruising or swelling.
- Rare erectile rigidity changes, treatable with PDE5 inhibitors.
Importantly, no permanent dysfunction has been reported with skilled surgeons.
Treatment Comparison
Treatment | Success Rate | Duration | Downsides |
---|---|---|---|
Sexual Therapy | 40–60% | Variable | Relapse risk, limited effect |
Topical Creams & Sprays | 50–60% | Short-term | Partner numbness, reduced pleasure |
Oral Medications (SSRIs) | 60–70% | During use | Side effects, dependency |
Hyaluronic Acid Injections | ~70% | 6–12 months | Repeat needed, uneven results |
Selective Dorsal Cryoablation | 90–95% | 1–2 years+ | Expertise required, specialized centers |
Why SDC May Be the Future
Selective Dorsal Cryoablation stands out for many reasons:
- Directly targets hypersensitive penile nerves.
- Provides long-lasting results without daily drugs.
- Reversible and repeatable.
- High patient satisfaction rates.
Patient Experience and Recovery
- During procedure: Minimal pain due to local anesthesia.
- After procedure: Tingling or slight discomfort may last 1–2 weeks.
- Return to sex: Often the same day or next day.
- Long-term results: Brain adapts, leading to durable control.

Conclusion
From its early use in the 1960s, cryoablation has evolved into a safe, precise, and effective method. In premature ejaculation treatment, Selective Dorsal Cryoablation is showing exceptional promise.
For men in the USA, Canada, UK, and Europe, SDC offers a permanent, drug-free solution when traditional therapies fail.
📞 Contact us today to learn if cryoablation is right for you.
References
- Cooper IS, et al. Use of liquid nitrogen for cryotherapy. 1961.
- Amoils SH. Application of CO₂ and N₂O in cryosurgery. 1967.
- Lloyd JW, et al. Effects of low temperature on peripheral nerves. 1976.
- Prologo JD. Pilot study on cryoablation for premature ejaculation. 2013.
- McMahon CG, et al. Disorders of Ejaculation: AUA/SMSNA Guideline. J Urol. 2021.
- Abdel-Hamid IA, et al. Hyaluronic Acid Injection Therapy for PE. Sex Med Rev. 2020.
- Yang DY, et al. Botulinum Toxin Injection in Glans Penis for PE. Int J Impot Res. 2008.
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